Statement of Retraction: Cu(II)-based coordination polymers: treatment activity on Takayasu’s arteritis via regulating protein-arginine deiminase content

Anti-tumor activity of arginine deiminase via arginine deprivation in retinoblastoma.

In spite of recent advances in the treatment of retinoblastoma, chemotherapy is still challenging in high-stage intraocular retinoblastoma or metastatic retinoblastoma. Here, we investigated whether arginine deprivation via arginine deiminase (ADI) could be a new anti-tumor therapy in retinoblastoma cells. Expression of argininosuccinate synthetase (ASS) was detected in human retinoblastoma tis...

Pre-pulseless and Pulseless Takayasus' Arteritis

The Confused Terminology and Changing Concept of Takayasu's Arteritis In 1908 the Japanese opihthalmologist, Takayasu, reported an unusual wreath-like vascular anastomosis surrounding the optic discs of a young female patient who was nearly iblind, biut who showed 'no general physical changes'. He was unalble to explain this abnormality. Laiter a colleague, Onishi, referred to a similar case wh...

Perspective on Protein Arginine Deiminase Activity—Bicarbonate Is a pH-Independent Regulator of Citrullination

Protein citrullination catalyzed by peptidyl arginine deiminase (PADs) is involved in autoimmune disease pathogenesis, especially in rheumatoid arthritis. Calcium is a key regulator of PAD activity, but under normal physiological conditions it remains uncertain how intracellular calcium levels can be raised to sufficiently high levels to activate these enzymes. In pursuit of trying to identify ...

Monitoring of protein arginine deiminase activity by using fluorescence quenching: multicolor visualization of citrullination.

Takayasus Arteritis in Children: A Developing World Perspective

Received: Nov 25, 2013 Accepted: Dec 03, 2013 Ann Paediatr Rheum 2013;2:134-146 DOI: 10.5455/apr.120320130832 Introduction Takayasus Arteritis (TA) is a large vessel granulomatous vasculitis affecting the Aorta and its main branches. This disease has remained enigmatic since its ocular signs were first described in a young woman, by Japanese ophthalmologist Mikito Takayasu in 1908 [though it ha...